(N/A) Pancreatic juice is a vital digestive secretion produced by the pancreas and released into the duodenum. It contains several inactive enzymes, active enzymes, and bicarbonate ions.
$1$. Inactive Enzymes (Zymogens): These include $Trypsinogen$, $Chymotrypsinogen$, and $Procarboxypeptidases$. $Trypsinogen$ is activated by $Enterokinase$ (secreted by the intestinal mucosa) into $Trypsin$, which subsequently activates the other zymogens.
$2$. Active Enzymes:
- $Pancreatic \text{ } Amylase$: Hydrolyzes polysaccharides (starch) into disaccharides.
- $Pancreatic \text{ } Lipase$: Acts on emulsified fats to break them down into diglycerides and monoglycerides.
- $Nucleases$: Break down nucleic acids ($DNA$ and $RNA$) into nucleotides and nucleosides.
$3$. Bicarbonate Ions: These provide an alkaline $pH$ (approximately $7.8 - 8.4$) to the chyme, which is necessary for the optimal activity of pancreatic enzymes and to neutralize the acidic chyme coming from the stomach.